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妊娠早期宫颈内应用前列腺素F2-α凝胶的有效性及副作用(作者译)

[Effectiveness and side-effects of intracervical application of prostaglandin F2-alpha-gel in the early weeks of pregnancy (author's transl)].

作者信息

Neeb U

出版信息

Geburtshilfe Frauenheilkd. 1980 Oct;40(10):901-3. doi: 10.1055/s-2008-1037237.

Abstract

In the Womens Hospital Peine from July 1, 1976 to December 31, 1979 503 artificial abortions were carried out by intracervical application of 3 mg PGF2-Alpha-Gel. In 82.5% of the cases patients had a spontaneous abortion or a cervical dilatation. Gastrointestinal side-effects were observed in 10.5% of the cases. 27.6% of the patients complained of acute pain. Complications due to the following mechanical dilatation did not occur. In three cases patients went into a state of shock after the gel-application. This, however, was quickly reversible. A systemic reaction an occur when PGF2-Gel is applied locally.

摘要

1976年7月1日至1979年12月31日期间,在派内妇女医院,对503例患者采用宫颈内应用3毫克前列腺素F2α凝胶的方法进行人工流产。82.5%的病例中患者出现自然流产或宫颈扩张。10.5%的病例观察到胃肠道副作用。27.6%的患者主诉急性疼痛。未发生因后续机械扩张导致的并发症。3例患者在应用凝胶后进入休克状态。不过,这种情况很快可逆转。局部应用前列腺素F2凝胶时可能会发生全身反应。

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