Beck B
Int J Androl. 1980 Aug;3(4):349-62. doi: 10.1111/j.1365-2605.1980.tb00124.x.
The effect of androgens on phospholipase A in the rat epididymis, liver, heart, kidney, prostate and epididymal fat pad has been investigated both in the cytosol and in a postmitochondrial particulate cell fraction. In both cell fractions, phospholipase A activity was 10-15 times higher in the cauda epididymidis than in the other organs, including the caput epididymidis, while the corpus showed an intermediate activity. In the cauda and corpus, castration reduced phospholipase A activity in both subcellular fractions to the same level as found in the other organs, and testosterone supplementation restored the enzyme activity. No evidence of a similar androgen controlled phospholipase A was found in any other tissue examined, including the prostate.
雄激素对大鼠附睾、肝脏、心脏、肾脏、前列腺和附睾脂肪垫中磷脂酶A的影响已在细胞溶质和线粒体后微粒体细胞组分中进行了研究。在这两种细胞组分中，附睾尾部的磷脂酶A活性比包括附睾头部在内的其他器官高10 - 15倍，而附睾体部则呈现中间活性。在附睾尾部和体部，去势使两个亚细胞组分中的磷脂酶A活性降低到与其他器官相同的水平，补充睾酮可恢复酶活性。在所检查的任何其他组织（包括前列腺）中均未发现类似的雄激素控制的磷脂酶A的证据。
