Epstein R A, Epstein M A, Haddad G G, Mellins R B
J Appl Physiol Respir Environ Exerc Physiol. 1980 Dec;49(6):1107-15. doi: 10.1152/jappl.1980.49.6.1107.
The barometric method is unique in permitting measurement of tidal volume in a totally noninvasive manner. Its application and accuracy have been limited by several complex problems. These include control of inspired gas composition, base-line stability, and asymmetry of processes occurring during inspiration and expiration. A new method is described that addresses these problems and facilitates long-term measurements. New calculations, which avoid previous errors that caused the method to systematically underestimate tidal volume, are illustrated.