Valdez H, Clark R G, Hanselka D V
J Am Vet Med Assoc. 1980 Sep 1;177(5):427-35.
Flexible medical grade carbon fiber was surgically implanted in tenectomized or lacerated superficial and deep digital flexor tendons of 13 horses (7 clinical cases and 6 experimental), ranging in age from 15 months to 10 years and weighing 300 to 500 kg. The 6 experimental horses were euthanatized at 30-, 45-, 60-, and 90-day intervals for gross and histologic evaluation of the results. Three of the experimental horses served as their own controls. Of the 7 clinically affected horses, 3 were euthanatized because they developed laminitis or the wound failed to heal. The remaining 4 horses in that group were discharged; 3 returned to their previous activities, and 1 was unavailable for follow-up. Carbon fiber produced a structure of approximately the same size and function as a normal tendon. Histologically, the fibroblasts and collagen fibers organized and aligned themselves in the early stages of healing. The implants appeared grossly and histologically to produce a cosmetically acceptable, strong, and functional tendon.
将柔性医用级碳纤维通过手术植入13匹马(7例临床病例和6例实验病例)的指浅屈肌腱和指深屈肌腱切断或撕裂处,这些马的年龄在15个月至10岁之间,体重300至500千克。6例实验马在30天、45天、60天和90天的间隔期实施安乐死,以便对结果进行大体和组织学评估。其中3例实验马作为自身对照。7例临床患病马中,3例因发生蹄叶炎或伤口未愈合而实施安乐死。该组其余4匹马出院;3匹马恢复了先前的活动,1匹马无法进行随访。碳纤维产生的结构在大小和功能上与正常肌腱大致相同。在组织学上,成纤维细胞和胶原纤维在愈合早期自行组织并排列。植入物在大体和组织学上似乎产生了一个在外观上可接受、坚固且有功能的肌腱。