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发育中小鼠小脑平行纤维的瞬时伴刀豆球蛋白A结合糖蛋白:其聚糖被破坏的证据

Transient concanavalin A-binding glycoproteins of the parallel fibres of the developing rat cerebellum: evidence for the destruction of their glycans.

作者信息

Reeber A, Vincendon G, Zanetta J P

出版信息

J Neurochem. 1980 Dec;35(6):1273-7. doi: 10.1111/j.1471-4159.1980.tb08998.x.

DOI:10.1111/j.1471-4159.1980.tb08998.x
PMID:7441249
Abstract

The lifetime of the glycoprotein glycans of the rat cerebellum was followed in the 2nd and 3rd weeks of postnatal age, after injection of labelled glucosamine. It appears that a particular class of glycans binding to Concanavalin A synthesized at an early age has a short lifetime. These results indicate that the glycans of the concanavalin A-binding glycoproteins abundant on the newly formed parallel fibres are rapidly degraded between the 14th and the 18th postnatal day.

摘要

在注射标记的葡糖胺后,对出生后第2周和第3周大鼠小脑糖蛋白聚糖的寿命进行了跟踪研究。结果显示,一类在早期合成的、与伴刀豆球蛋白A结合的特定聚糖寿命较短。这些结果表明,在新生平行纤维上大量存在的伴刀豆球蛋白A结合糖蛋白的聚糖在出生后第14天到第18天之间迅速降解。

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Transient concanavalin A-binding glycoproteins of the parallel fibres of the developing rat cerebellum: evidence for the destruction of their glycans.发育中小鼠小脑平行纤维的瞬时伴刀豆球蛋白A结合糖蛋白:其聚糖被破坏的证据
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Intrinsic and extrinsic determinants of neuronal development: relation to infantile autism.神经元发育的内在和外在决定因素:与婴儿自闭症的关系。
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