Iritani N, Fukuda E, Inoguchi K
J Nutr Sci Vitaminol (Tokyo). 1980;26(3):271-7. doi: 10.3177/jnsv.26.271.
The effects of fasting and refeeding on hepatic Z protein were investigated in rats. When [U-14C]palmityl-CoA was added to the liver cytosol fraction from fat-free refed rats, more binding of labeled palmityl-CoA to the Z-protein region was found than in the case of fasted rats. Also the radioactivities in specific precipitations of the palmityl-CoA binding protein with anti-Z immunoglobulin G were higher in the refed rats. The Z protein which stimulated diacylglycerol acyltransferase may be involved in the change of triacylglycerol synthesis in fasted and refed rat livers.
在大鼠中研究了禁食和再喂养对肝脏Z蛋白的影响。当将[U-14C]棕榈酰辅酶A添加到无脂肪再喂养大鼠的肝脏胞质溶胶部分时，发现标记的棕榈酰辅酶A与Z蛋白区域的结合比禁食大鼠的情况更多。再喂养大鼠中棕榈酰辅酶A结合蛋白与抗Z免疫球蛋白G的特异性沉淀中的放射性也更高。刺激二酰基甘油酰基转移酶的Z蛋白可能参与禁食和再喂养大鼠肝脏中三酰甘油合成的变化。
