牛角膜上皮中的雄激素代谢
Androgen metabolism in the epithelium of the bovine cornea.
作者信息
Ploc I, Sulcová J, Stárka L
出版信息
Endokrinologie. 1978 Nov;72(3):327-33.
PMID:744178
Abstract
The metabolism of [14C]-testosterone and [14C]-androstenedione resp. was investigated in the epithelium of the cow cornea. [14C]-testosterone was converted mainly to androstenedione (48.3%), while conversion to dihydrotestosterone accounted only for 2%. On incubation of androstenedione mainly testosterone was formed (9.8%) and polar, probably hydroxylated, substances (7.6%).
摘要
分别对[14C] - 睾酮和[14C] - 雄烯二酮在牛眼角膜上皮中的代谢进行了研究。[14C] - 睾酮主要转化为雄烯二酮（48.3%），而转化为二氢睾酮的比例仅为2%。雄烯二酮孵育时，主要生成睾酮（9.8%）和极性物质（可能是羟基化产物，7.6%）。
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