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手术创伤和热烧伤对人体锌代谢的不同影响。

Differential effect of surgical injury and thermal burn on zinc metabolism in man.

作者信息

Mountokalakis T, Voyatzoglou V, Boukis D, Tsata-Voyatzoglou V, Koutselinis A, Merikas G

出版信息

Klin Wochenschr. 1980 Jul 1;58(13):695-7. doi: 10.1007/BF01478607.

DOI:10.1007/BF01478607
PMID:7442082
Abstract

Serum, erythrocyte and urinary zinc were serially measured during the early ten days following major surgery or thermal burns in 18 and 8 patients, respectively. Serum zinc gradually decreased and erythrocyte and urinary zinc increased during the first three postoperative or post-burn days. Thereafter, both serum and erythrocyte zinc gradually returned to preoperative levels in the patients subjected to surgery, while serum zinc continued to fall progressively despite a rapid restoration of erythrocyte zinc to control values, in the burned patients. It is suggested that in contrast to the early postoperative or post-burn hypozincemia, which may be attributed to a redistribution of zinc from plasma to tissue, continued decrease in serum zinc following thermal burns may indicate a mobilization of zinc to the burn site and eventually result in significant zinc depletion.

摘要

分别对18例接受大手术的患者和8例烧伤患者在术后或烧伤后的前十天连续测量血清、红细胞和尿锌。在术后或烧伤后的头三天,血清锌逐渐下降,红细胞和尿锌增加。此后,接受手术的患者血清和红细胞锌均逐渐恢复到术前水平,而烧伤患者尽管红细胞锌迅速恢复到对照值,但血清锌仍继续逐渐下降。这表明,与术后早期或烧伤后低锌血症(可能归因于锌从血浆重新分布到组织)不同,烧伤后血清锌持续下降可能表明锌被动员到烧伤部位,并最终导致明显的锌缺乏。

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1
Differential effect of surgical injury and thermal burn on zinc metabolism in man.手术创伤和热烧伤对人体锌代谢的不同影响。
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本文引用的文献

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2
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Effects of long-continued ingestion of zinc sulphate in patients with venous leg ulceration.长期摄入硫酸锌对下肢静脉溃疡患者的影响。
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[Evolution of serum copper and zinc levels in burn patients (author's transl)].烧伤患者血清铜和锌水平的变化(作者译)
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Changes in serum zinc during and after surgical procedures.手术过程中和术后血清锌的变化。
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