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In vivo changes in the GABA content of nerve endings (synaptosomes) induced by inhibitors of GABA uptake.

作者信息

Wood J D, Schousboe A, Krogsgaard-Larsen P

出版信息

Neuropharmacology. 1980 Nov;19(11):1149-52. doi: 10.1016/0028-3908(80)90117-3.

DOI:10.1016/0028-3908(80)90117-3
PMID:7442946
Abstract
摘要

相似文献

1
In vivo changes in the GABA content of nerve endings (synaptosomes) induced by inhibitors of GABA uptake.γ-氨基丁酸摄取抑制剂诱导的神经末梢（突触体）γ-氨基丁酸含量的体内变化
Neuropharmacology. 1980 Nov;19(11):1149-52. doi: 10.1016/0028-3908(80)90117-3.
2
[Nipecotic acid, a competitive inhibitor of the net uptake of 3H-GABA by rat brain synaptosomes].[尼克酸，大鼠脑突触体对3H-GABA净摄取的竞争性抑制剂]
Biull Eksp Biol Med. 1981 Jun;91(6):692-4.
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Effects of intravenous general anesthetics on [3H]GABA release from rat cortical synaptosomes.静脉全身麻醉药对大鼠皮质突触体[3H]γ-氨基丁酸释放的影响。
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Coexistence of carriers for dopamine and GABA uptake on a same nerve terminal in the rat brain.大鼠脑中同一神经末梢上多巴胺和γ-氨基丁酸摄取载体的共存。
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Release-regulating autoreceptors of the GABAB-type in human cerebral cortex.人类大脑皮层中GABAB型释放调节自身受体
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gamma-Aminobutyric acid (GABA) stimulates somatostatin release following activation of a GABA uptake carrier located on somatostatin nerve endings of rat cerebral cortex.γ-氨基丁酸（GABA）在激活位于大鼠大脑皮质生长抑素神经末梢上的GABA摄取载体后，刺激生长抑素释放。
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Effect of taurine on neurotransmitter release from insect synaptosomes.
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Effects of beta-alanine, L-2,4-diaminobutyric acid and nipecotic acid on the sodium-dependent binding of [3H]GABA to brain particles.β-丙氨酸、L-2,4-二氨基丁酸和哌啶酸对[3H]GABA与脑微粒体钠依赖性结合的影响。
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(R)-N-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]nipecotic acid binds with high affinity to the brain gamma-aminobutyric acid uptake carrier.（R）-N-[4,4-双（3-甲基-2-噻吩基）丁-3-烯-1-基]哌啶酸与脑γ-氨基丁酸摄取载体具有高亲和力结合。
J Neurochem. 1990 Feb;54(2):639-47. doi: 10.1111/j.1471-4159.1990.tb01919.x.

引用本文的文献

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The GABA synapse as a target for antiepileptic drugs: a historical overview focused on GABA transporters.作为抗癫痫药物靶点的GABA突触：聚焦于GABA转运体的历史概述
Neurochem Res. 2014 Oct;39(10):1980-7. doi: 10.1007/s11064-014-1263-9. Epub 2014 Mar 14.
2
Relationship between drug-induced changes in seizure thresholds and the GABA content of brain and brain nerve endings.药物诱导的癫痫阈值变化与脑及脑神经末梢中γ-氨基丁酸含量之间的关系。
Naunyn Schmiedebergs Arch Pharmacol. 1981 Sep;317(2):131-4. doi: 10.1007/BF00500068.
3
Comparison between (RS)-nipecotic acid and GABA transport in cultured astrocytes: coupling with two sodium ions.
培养星形胶质细胞中（RS）-哌啶酸与γ-氨基丁酸转运的比较：与两个钠离子的偶联
Neurochem Res. 1981 Mar;6(3):257-66. doi: 10.1007/BF00964041.
4
Amplification by glycine of the effect of the GABA transport inhibitor THPO on synaptosomal GABA level.
Neurochem Res. 1988 Oct;13(10):917-21. doi: 10.1007/BF00970762.
5
GABA receptor binding site "induction" in rabbit retina after nipecotic acid treatment: changes during postnatal development.
Neurochem Res. 1986 Jan;11(1):55-61. doi: 10.1007/BF00965165.