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与严重脑水肿相关的脑膜瘤中的血管成分。

The vascular component in meningiomas associated with severe cerebral edema.

作者信息

Challa V R, Moody D M, Marshall R B, Kelly D L

出版信息

Neurosurgery. 1980 Oct;7(4):363-8. doi: 10.1227/00006123-198010000-00009.

Abstract

Cerebral edema is usually a complication of the later growth stages of intracranial neoplasms. Three patients with small meningiomas presented with unusually several cerebral edema out of proportion to the size of tumors. All three tumors exhibited benign meningothelial components, the formation of pseudopsammoma bodies, and striking vascular mural proliferation of small dark cells. In two tumors ultrastructural examination of these cells showed features of pericytes. The vascular pericytic component in these tumors may grow more actively than the meningothelial component and thus may cause the production of severe cerebral edema. The clinical, radiological, operative, and light and electron microscopic findings are presented, and the relationship to angioblastic meningiomas is discussed.

摘要

脑水肿通常是颅内肿瘤生长后期的一种并发症。三名患有小型脑膜瘤的患者出现了与肿瘤大小不成比例的异常严重脑水肿。所有三个肿瘤均表现出良性脑膜内皮成分、假砂粒体形成以及小暗细胞显著的血管壁增生。在两个肿瘤中,对这些细胞的超微结构检查显示出周细胞的特征。这些肿瘤中的血管周细胞成分可能比脑膜内皮成分生长更活跃,从而可能导致严重脑水肿的产生。本文介绍了临床、放射学、手术以及光镜和电镜检查结果,并讨论了与成血管细胞性脑膜瘤的关系。

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