Miner M E, Rea G L, Handel S, Bertz J
Neuroradiology. 1980;20(3):163-6. doi: 10.1007/BF00341782.
Ectrodactyly (lobster claw deformity), ectodermal dysplasia and clefting of the lip or palate, the EEC syndrome, is a rare genetic disorder involving both mesodermal and ectodermal derivatives. Cerebral arterial dolichoectasia, a pathological dilatation and elongation of intracranial vessels, was found in a patient with the EEC syndrome. Her hypertensive cardiovascular disease, mild dementia and trigeminal neuralgia were all related to her dolichoectasia. Although the association of dolichoectasia has not been previously observed with the EEC syndrome, it may be more frequent than currently recognized. Cerebral arterial dolichoectasia and its attendant sequelae could account for some of the unexplained abnormalities described in other case reports of patients with the EEC syndrome.
缺指（趾）畸形（龙虾爪样畸形）、外胚层发育不良以及唇腭裂，即EEC综合征，是一种涉及中胚层和外胚层衍生物的罕见遗传性疾病。在一名EEC综合征患者中发现了脑动脉延长扩张症，即颅内血管的病理性扩张和伸长。她的高血压性心血管疾病、轻度痴呆和三叉神经痛均与她的动脉延长扩张症有关。尽管此前未观察到动脉延长扩张症与EEC综合征相关联，但实际情况可能比目前所认识到的更为常见。脑动脉延长扩张症及其伴随的后遗症可能是EEC综合征其他病例报告中所描述的一些无法解释的异常情况的原因。
