Ugriumov M V, Chandrasekkhar K
Ontogenez. 1980;11(4):351-8.
The tanycyte differentiation during the perinatal period was studied by means of electron microscope in rats. From the 16th till the 18th day of prenatal period the wall of the 3rd ventricle is formed by intensively proliferating matrix cells with a narrow long apical process, oval perykarya and basal process. As the differentiation proceeds, the apical process shortens and disappears. The number of such cells increases gradually. At the same time the concentration of rough endoplasmic reticulum, mitochondria, polysomes, lipid droplets, dense, lamellated and multivesicular bodies increases. By the 3rd day the proliferative activity of cells decreases and they differ markedly in the ventral and ventrolateral parts of the infundibular recess and in the periphery of its broadened part. After the 5th day the ultrastructure of tanycytes and character of their distribution within the infundibular recess practically do not change, thus witnessing indirectly the completion of the main stages of differentiation of these cells.
采用电子显微镜技术对大鼠围生期的伸展细胞分化进行了研究。在产前第16天至18天,第三脑室壁由密集增殖的基质细胞构成,这些细胞具有狭窄的长顶突、椭圆形的核周体和基底突。随着分化的进行,顶突缩短并消失。这类细胞的数量逐渐增加。与此同时,粗面内质网、线粒体、多核糖体、脂滴、致密体、板层体和多囊泡体的浓度增加。到第3天时,细胞的增殖活性降低,它们在漏斗隐窝的腹侧和腹外侧部分及其扩大部的周边有明显差异。第5天后,伸展细胞的超微结构及其在漏斗隐窝内的分布特征实际上没有变化,从而间接证明了这些细胞分化主要阶段的完成。