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手术或放疗后上肢淋巴水肿。间接放射性淋巴造影检查(作者译)

[Lymphoedema of the upper limb following surgery or radiotherapy. Investigation by indirect radioactive lymphography (author's transl)].

作者信息

Pecking A, Firmin F, Rain J D, Desprez-Curely J P, Cluzan R, Jacquillat C, Banzet P

出版信息

Nouv Presse Med. 1980 Nov 22;9(44):3349-51.

PMID:7443487
Abstract

Indirect radioactive isotope lymphography using intravenous 99 m Tc-labelled colloidal antimony sulfide was performed on 76 patients with lymphoedema of the upper limb consecutive to surgery or radiotherapy. The time required to reach 50% of maximum radioactivity was taken as index of the lymphatic flow rate, and the patients were divided into 3 groups depending upon the index (< 20 min; 20-60 min; > 60 min). It appears that in huge lymphoedemas the lymphatic flow rate index may remain subnormal, owing to associated veno-occlusive oedema. This non-invasive method provides data on the site and, frequently, on the nature and importance of lymph blockade. It might also help to predict the efficacy of a new drug currently under study.

摘要

对76例因手术或放疗导致上肢淋巴水肿的患者进行了间接放射性同位素淋巴造影,采用静脉注射99m锝标记的硫化锑胶体。将达到最大放射性50%所需的时间作为淋巴流速指标,根据该指标将患者分为3组(<20分钟;20 - 60分钟;>60分钟)。结果显示,在巨大淋巴水肿中,由于合并静脉阻塞性水肿,淋巴流速指标可能仍低于正常水平。这种非侵入性方法可提供关于淋巴阻塞部位的数据,并且常常能提供关于淋巴阻塞的性质和严重程度的数据。它还有助于预测目前正在研究的一种新药的疗效。

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