人胎盘合体滋养层母体血表面的连接结构

Junctions on the maternal blood surface of the human placental syncytium.

作者信息

Reale E, Wang T, Zaccheo D, Maganza C, Pescetto G

出版信息

Placenta. 1980 Jul-Sep;1(3):245-58. doi: 10.1016/s0143-4004(80)80006-3.

Abstract

Terminant chorionic villi of the human placenta at 8, 9, 12, 14 weeks' gestation and at full term have been studied in freeze-fracture replicas and in thin sections. In replicas, maculae occludentes of different size have been detected in all placental samples on the cleaved plasma membrane of the free (maternal) surface of the syncytiotrophoblast. In thin sections they are located in narrow invaginations of the syncytium luminal plasma membrane. These invaginations are in turn similar to flattened vesicles (also associated with junctions) located in the underlying syncytioplasm. Possible origin and function of the junctions on the syncytium free surface are discussed.

摘要

对妊娠8周、9周、12周、14周及足月时的人胎盘终末绒毛进行了冷冻断裂复型和薄切片研究。在复型中，在所有胎盘样本的合体滋养层游离（母体）表面劈开的质膜上检测到了不同大小的紧密连接斑。在薄切片中，它们位于合体细胞腔面膜的狭窄内陷处。这些内陷又类似于位于其下合体细胞质中的扁平小泡（也与连接有关）。讨论了合体细胞游离表面连接的可能起源和功能。