Nosko M
Probl Khig. 1980;5:92-7.
Experimental investigations were undertaken to establish the acute and subacute inhalatory, oral and dermal toxicity of glycolmonophosphate. Modern toxicologic, biochemical and pathomorphologic methods were used. It was found that glucomonoacetate has a mild acute and subacute inhalatory, oral and dermal toxicity. The changes in some enzyme activities (GOT, GPT, AP, HE) and the parenchymatous dystrophy of the liver are considered transient and of functional nature. The toxic effect of glucomonoacetate is studied for the first time. Its use in the production of cigarette filters has a definite economical effect.
开展了实验研究以确定磷酸单糖酯的急性和亚急性吸入、口服及经皮毒性。采用了现代毒理学、生物化学和病理形态学方法。结果发现，葡萄糖单乙酸酯具有轻度的急性和亚急性吸入、口服及经皮毒性。一些酶活性（谷草转氨酶、谷丙转氨酶、碱性磷酸酶、羟脯氨酸酶）的变化以及肝脏实质营养不良被认为是短暂的且具有功能性。葡萄糖单乙酸酯的毒性作用首次得到研究。其在香烟过滤嘴生产中的应用具有一定的经济效益。
