Prasad R, Rao Y V, Sindhu R K, Subrahmanyam D
Trans R Soc Trop Med Hyg. 1980;74(4):459-62. doi: 10.1016/0035-9203(80)90055-3.
Pyridoxine deficiency has been induced in albino rats at the weanling or neonatal stages. Exposure of the vitamin-deficient rats to the infective larvae of Litomosoides carinii resulted in no development or establishment of the parasite in the host. Although the food consumption of the pair-fed group was necessarily restricted to that of the deficient group, the susceptibility of the animals of the pair-fed group receiving the normal vitamin intake resembled that of the control group. The humoral immune response to the infection in the pair-fed controls as measured by indirect haemagglutination, was inhibited compared to that in the controls. This inhibition was more severe in the vitamin-deficient animals.
在白化大鼠的断奶期或新生期诱导了维生素B6缺乏。将缺乏维生素的大鼠暴露于卡里尼氏丝虫的感染性幼虫中，寄生虫在宿主体内未发育或未定植。尽管配对喂养组的食物摄入量必然限制在缺乏组的水平，但接受正常维生素摄入量的配对喂养组动物的易感性与对照组相似。通过间接血凝测定，配对喂养对照组对感染的体液免疫反应与对照组相比受到抑制。这种抑制在维生素缺乏的动物中更严重。
