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[六周维生素A缺乏饮食对内耳感觉细胞的影响。光镜和电镜研究]

[Effect of a 6-week vitamin A-deficient diet on the sensory cells of the inner ear. Light and electron microscopic studies].

作者信息

Löhle E

出版信息

Z Ernahrungswiss. 1980 Sep;19(3):203-14. doi: 10.1007/BF02018786.

Abstract

Histologic studies of the inner ear in rats with chronic vitamin A deficiency have produced contradicting results. In our own electronmicroscope investigations of the inner ear of young rats after a six week vitamin A deficit diet we found a lacking of the cuticle in the outer hair cells and a subtotally lacking of the cuticle in the inner hair cells. Furthermore, we found changes in the reticular system of the intermediate zone. These morphologic changes together with the recent findings of high concentrations of vitamin A in the corti organ support the hypothesis that the acoustic sensory receptors contain or functionally depend upon vitamin A.

摘要

对慢性维生素A缺乏大鼠内耳的组织学研究得出了相互矛盾的结果。在我们自己对幼鼠进行六周维生素A缺乏饮食后内耳的电子显微镜研究中,我们发现外毛细胞的角质膜缺失,内毛细胞的角质膜部分缺失。此外,我们还发现中间区网状系统有变化。这些形态学变化以及最近在柯蒂氏器中发现的高浓度维生素A,支持了听觉感觉受体含有维生素A或在功能上依赖维生素A这一假说。

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