Ilyés I, Péter F
Acta Paediatr Acad Sci Hung. 1980;21(1):65-7.
Serum reverse T3, T3, T4, and TSH concentrations were measured in children with goitre of grade II and III, and in controls of the same age. The average rT3 level was decreased in both goitrous groups and the difference between them was significant. The rT3/T4 ratio in each group changed in a similar way. It seems that in goitre not only the T3 secretion of the thyroid gland is increased but also the deiodination of T4 to T3 increases against rT3, or the degradation and metabolic clearance of T3 and rT3 change.
对患有II级和III级甲状腺肿的儿童以及同龄对照组测定血清反三碘甲状腺原氨酸(rT3)、三碘甲状腺原氨酸(T3)、甲状腺素(T4)和促甲状腺激素(TSH)浓度。两个甲状腺肿组的平均rT3水平均降低,且两组之间的差异具有显著性。每组的rT3/T4比值变化方式相似。似乎在甲状腺肿中,不仅甲状腺的T3分泌增加,而且T4向T3的脱碘相对于rT3增加,或者T3和rT3的降解及代谢清除发生了变化。