Kjaergaard J, Jensen H E, Allermand H
Ann Surg. 1980 Dec;192(6):711-5. doi: 10.1097/00000658-198012000-00003.
In a study of 545 patients who underwent vagotomies for repair of duodenal ulcers, 62 patients (11%) were found to have inadequately reduced pentapeptide and/or insulin-stimulated acid secretions three months after operation. The ulcers recurred in 14 patients within three to nine years (mean: four years) (23%, 95% confidence limits: 13-35). Postoperative acid production and acid reduction were equal in patients with and without ulcer recurrence. The patients who did not develop recurrent ulcers had significantly lower preoperative pentapeptide peak acid outputs and significantly shorter preoperative histories of ulcers than patients whose ulcers recurred.
在一项针对545例因十二指肠溃疡修复而接受迷走神经切断术的患者的研究中，发现62例患者（11%）在术后三个月时五肽和/或胰岛素刺激的胃酸分泌减少不充分。14例患者的溃疡在三至九年（平均：四年）内复发（23%，95%置信区间：13 - 35）。有溃疡复发和无溃疡复发的患者术后胃酸分泌量和胃酸分泌减少程度相当。未发生溃疡复发的患者术前五肽峰值胃酸排出量显著更低，且术前溃疡病史显著短于溃疡复发的患者。
