Brief clinical characteristics and microscopic structure of a peculiar focal granulomatosis, macrophagal affection of the urinary bladder mucous membrane, are described. Microscopically, malacoplakia of the urinary bladder has a zonal structure the presence of which is important for differential diagnosis from some tumours, particularly myoma consisting of myoblasts and malignant histiocytoma. The presence of small rounded basophilic inclusions (Mikhaelis--Gutmann bodies) is a characteristic feature of malacoplakia.
本文描述了一种特殊的局灶性肉芽肿(膀胱黏膜巨噬细胞病变)的简要临床特征和微观结构。在显微镜下,膀胱软斑病具有带状结构,这一结构的存在对于与某些肿瘤,特别是由成肌细胞组成的肌瘤和恶性组织细胞瘤进行鉴别诊断很重要。小的圆形嗜碱性包涵体(米夏埃利斯-古特曼小体)的存在是软斑病的特征性表现。