Kelly M P, Garron D C, Javid H
Arch Neurol. 1980 Dec;37(12):743-8. doi: 10.1001/archneur.1980.00500610023002.
Thirty-five carotid endarterectomy patients and 17 peripheral vascular surgery controls were evaluated psychologically preoperatively and postoperatively. The endarterectomy sample was restricted to patients with transient ischemic attacks. Neuropsychological tests included measures of language, attention, memory, problem solving, and sensory and motor skills. Personality tests included measures of general psychopathology, with specific evaluation of anxiety and depression. Mean scores of the endarterectomy and control groups were not statistically significantly different preoperatively for any test. Postoperatively, only the endarterectomy group showed mean improvement on measures of memory and verbal fluency. Both groups showed improvement on several other neuropsychological measures, and in reduction in state anxiety and on another indicator of psychopathology. Endarterectomy patients whose cognition improved postoperatively were younger, better educated, and had lower admitting systolic blood pressure; they also tended to have a lesser incidence of generalized vascular disease.
对35例接受颈动脉内膜切除术的患者和17例接受外周血管手术的对照者在术前和术后进行了心理评估。内膜切除术样本仅限于短暂性脑缺血发作患者。神经心理学测试包括语言、注意力、记忆、解决问题以及感觉和运动技能的测量。人格测试包括一般精神病理学测量,特别评估焦虑和抑郁。在内膜切除术组和对照组中,术前任何测试的平均得分在统计学上均无显著差异。术后,只有内膜切除术组在记忆和语言流畅性测量方面显示出平均改善。两组在其他几项神经心理学测量方面均有改善,且状态焦虑和另一种精神病理学指标有所降低。术后认知功能改善的内膜切除术患者更年轻、受教育程度更高、入院时收缩压更低;他们还往往患有全身性血管疾病的发生率较低。