Mikhal'tsev D L, D'iakonova T L, Nabokin P I, Gromenko D L, Maslov Iu A
Biofizika. 1980 Nov-Dec;25(6):1027-33.
The quasielectrostatic impact (QESI) on the electrical activity of an isolated neuron of mollusc was investigated. It was shown that QESI with the frequencies of (0.05--1) Hz controls the time pattern of the nerve cell electrical activity, producing the frequency modulation (FM) of action potentials (AP) in accordance with the frequency and field intensity applied. The threshold intensity of the transmembrane currents produced by QESI for FM AP effect of the spontaneously active neurorrs are of the order to 10(-13)--10(-12) A, while the threshold shifts of the membrane potentials for different cells vary as (10--100) muV. These figures correlate with the effective field intensity of the order of 0.1--1 V/m in the extracellular space under intact conditions. The obtained data are considered to be important for ephatic cellular interaction and the role of the low level slow potential shifts as the control factor in the formation of pulse activity time pattern of neurons of the intact brain.
研究了准静电冲击（QESI）对软体动物离体神经元电活动的影响。结果表明，频率为（0.05--1）Hz的QESI控制着神经细胞电活动的时间模式，根据所施加的频率和场强产生动作电位（AP）的频率调制（FM）。QESI产生的跨膜电流对自发活动神经元FM AP效应的阈值强度约为10^(-13)--10^(-12) A，而不同细胞的膜电位阈值变化为（10--100）μV。这些数值与完整条件下细胞外空间中约0.1--1 V/m的有效场强相关。所获得的数据被认为对于邻细胞相互作用以及低水平缓慢电位变化作为完整大脑神经元脉冲活动时间模式形成中的控制因素的作用具有重要意义。
