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[通过动静脉分流大量输注同源血液后人体血流动力学和氧气供应的变化]

[Changes in hemodynamics and oxygen supply to the body following massive administration of homologous blood by means of an arteriovenous shunt].

作者信息

Iarochkin V S, Gusenova F M

出版信息

Biull Eksp Biol Med. 1980 Nov;90(11):550-2.

PMID:7448387
Abstract

In experiments on dogs, exchange normovolemic perfusion of homologous blood by means of arteriovenous bypass resulted in disturbances of blood circulation and development of circulatory hypoxia. This was manifested in a significant slowing of the blood flow, a decrease in cardiac output an abrupt increase in general peripheral resistance that allowed arterial pressure to be maintained at a physiological level. Compensation of hypoxia occurred at the expense of a rise in O2 utilization from inflowing blood.

摘要

在对狗的实验中,通过动静脉旁路进行同源血液的等容交换灌注会导致血液循环紊乱和循环性缺氧的发生。这表现为血流显著减慢、心输出量减少、总外周阻力突然增加,从而使动脉血压维持在生理水平。缺氧的代偿是以流入血液中氧利用率的升高为代价的。

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