Kononova V A, Vtiurin B V
Biull Eksp Biol Med. 1980 Nov;90(11):616-9.
The myocardium of the right and left heart ventricles of rats was studied during 2.5-month adaptation to high-pressure chamber hypoxia (at an altitude of 6000 m). During varying time of rats' adaptation to hypoxia, destructive and compensatory-adaptive processes in the cardiomyocytes were seen concurrently. In long-term adaptation to high-pressure chamber hypoxia there developed hypertrophy largely of the heart right ventricle on account of hyperplasia and hypertrophy of individual intracellular organelles, particularly of mitochondria. The animals who adapted to high-pressure chamber hypoxia showed enhanced metabolic processes in the myocardium.
在对大鼠进行为期2.5个月的高压舱缺氧适应（海拔6000米）过程中，对其左右心室的心肌进行了研究。在大鼠适应缺氧的不同时间段内，心肌细胞中同时出现了破坏和代偿适应过程。在长期适应高压舱缺氧的过程中，由于单个细胞内细胞器，特别是线粒体的增生和肥大，心脏右心室出现了明显的肥大。适应高压舱缺氧的动物心肌中的代谢过程增强。
