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[暴露于霍乱毒素的乳兔小肠的扫描电子显微镜检查和X射线微分析]

[Scanning electron microscopy and x-ray microanalysis of the small intestine of suckling rabbits exposed to cholera toxin].

作者信息

Buravkov S V

出版信息

Biull Eksp Biol Med. 1980 Nov;90(11):622-6.

PMID:7448402
Abstract

Surface alterations and elemental distribution in small intestinal enterocytes of suckling rabbits were studied by scanning electron microscopy and x-ray microanalysis. The latter was performed on 10 mu thick freeze-dried cryosections. Cholera toxin was found to diminish the sodium and chloride content in the epithelial layer from the cryptae towards the tops of the villi, while in control animals, no difference in the elemental distribution was revealed. The changes in the enterocyte surface consisted in the disarrangement of the microvilli and appearance of bullous enlargements on their tops.

摘要

通过扫描电子显微镜和X射线微分析研究了哺乳兔小肠肠上皮细胞的表面变化和元素分布。后者是在10微米厚的冻干冷冻切片上进行的。发现霍乱毒素会降低从隐窝到绒毛顶部的上皮层中的钠和氯含量,而在对照动物中,未发现元素分布有差异。肠上皮细胞表面的变化包括微绒毛排列紊乱以及其顶部出现大疱样增大。

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