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[月经周期中人类子宫颈纤毛分泌上皮的演变。扫描电子显微镜研究]

[Evolution of human endocervical cilio-secretory epithelium during the menstrual cycle. Scanning electron microscopy study].

作者信息

Chrétien F C, Guillon G

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1978 Oct-Nov;7(7):1189-206.

PMID:744863
Abstract

The anatomy of the ventral epithelial surface of the human uterine endocervix was investigated by S.E.M. from biopsies taken at various periods of the menstrual cycle and from whole cervices obtained by hysterectomy on the 17th and 22nd day. Ciliated and secretory cells which constitute the epithelial surface appeared to be associated at random in various manners without apparent connection with the menstrual cycle. Considerable variation was observed at the same cycle period, depending on the patients. The release of mucus took place mainly according the macro-apocrine extrusion process, whose evolution was clear throughout menstrual cycle. Apocrine extrusions were found to be particularly intense and numerous from the 12th to the 16th day, with a peak on the 14th day. Some ciliated cells were also seen to exhibit protuberant mucus protrusion. The merocrine extrusion process was seen very rarely and thus seemed to be of minor importance. An evolutive provess also seems to occur at the level of ciliated cells: from the 9th to the 16th day, some secretory cells were seen to bear miniciliae of increasing length beside their typical microvillae. This could be interpreted as a transformation process of secretory into ciliated cells during the second third of the menstrual cycle.

摘要

利用扫描电子显微镜(S.E.M.)对取自月经周期不同阶段的活检组织以及在第17天和第22天通过子宫切除术获得的完整子宫颈进行研究,以观察人类子宫颈内膜腹侧上皮表面的解剖结构。构成上皮表面的纤毛细胞和分泌细胞似乎以各种方式随机分布,与月经周期没有明显联系。在同一周期阶段,根据患者不同观察到了相当大的差异。黏液的释放主要通过大顶浆分泌挤出过程进行,在整个月经周期中其演变过程清晰可见。发现顶浆分泌挤出在第12天至第16天特别强烈且数量众多,在第14天达到峰值。还观察到一些纤毛细胞呈现出突出的黏液突起。微分泌挤出过程很少见,因此似乎不太重要。在纤毛细胞水平似乎也发生了一个演变过程:从第9天到第16天,一些分泌细胞在其典型微绒毛旁边出现了长度不断增加的微纤毛。这可以解释为在月经周期的第二个三分之一期间分泌细胞向纤毛细胞的转化过程。

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1
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J Gynecol Obstet Biol Reprod (Paris). 1978 Oct-Nov;7(7):1189-206.
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