遗传对脑内儿茶酚胺的影响：盐敏感大鼠脑内去甲肾上腺素含量高
Genetic influence on brain catecholamines: high brain noradrenaline in salt-sensitive rats.
作者信息
Iwai J, Friedman R, Tassinari L
出版信息
Clin Sci (Lond). 1980 Dec;59 Suppl 6:263s-265s. doi: 10.1042/cs059263s.
PMID:7449267
Abstract
- Rats genetically sensitive to salt-induced hypertension showed higher levels of plasma noradrenaline and adrenaline than rats genetically resistant to hypertension. 2. The hypertension-sensitive rats had higher hypothalamic noradrenaline and lower adrenaline than resistant rats. 3. In response to a high salt diet brain-stem noradrenaline increased in sensitive rats and resistant rats exhibited a decrease on the same diet.
摘要
- 对盐诱导性高血压敏感的大鼠，其血浆去甲肾上腺素和肾上腺素水平高于对高血压有遗传抗性的大鼠。2. 高血压敏感型大鼠的下丘脑去甲肾上腺素水平高于抗性大鼠，而肾上腺素水平低于抗性大鼠。3. 对高盐饮食的反应中，敏感型大鼠脑干中的去甲肾上腺素增加，而抗性大鼠在相同饮食条件下该物质减少。
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