Carruth J E, Silverman M E
Chest. 1980 Dec;78(6):886-8. doi: 10.1378/chest.78.6.886.
We report the findings in a patient in whom prolongation of the Q-T interval and torsade de pointe ventricular tachycardia occurred as a complication of intracerebral and subarchnoid hemorrhage. The dysrhythmia did not recur after treatment with propranolol. Prolongation of the Q-T interval occurs frequently in patients with subarachnoid hemorrhage, causing a predisposition to torsade de pointe ventricular tachycardia. Propranolol, by blocking excessive sympathetic stimulation and shortening the Q-T interval, may be effective therapy for ventricular dysrhythmias associated with subarachnoid hemorrhage.
我们报告了1例脑内和蛛网膜下腔出血并发症出现Q-T间期延长和尖端扭转型室性心动过速患者的研究结果。用普萘洛尔治疗后心律失常未再复发。蛛网膜下腔出血患者常出现Q-T间期延长,易引发尖端扭转型室性心动过速。普萘洛尔通过阻断过度的交感神经刺激并缩短Q-T间期,可能是治疗与蛛网膜下腔出血相关的室性心律失常的有效疗法。