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心肺骤停与糖尿病自主神经病变

Cardiorespiratory arrest and diabetic autonomic neuropathy.

作者信息

Page M M, Watkins P J

出版信息

Lancet. 1978 Jan 7;1(8054):14-6. doi: 10.1016/s0140-6736(78)90360-4.

DOI:10.1016/s0140-6736(78)90360-4
PMID:74496
Abstract

Twelve cardiorespiratory arrests in eight neuropathy are reported. Only one patient died at the time, but two others subsequently died suddenly at home. There was no evidence of myocardial infarction, cardiac arrhythmia, or hypoglycaemia at the time of arrest. In most of the episodes there was some interference with respiration, either by anaesthesia, drugs, or bronchopneumonia. Five of the episodes occured during or immediately after anaesthesia. It is suggested that the arrests were caused by defective respiratory rather than cardiovascular reflexes. Cardiorespiratory arrest appears to be a specific feature of diabetic autonomic neuropathy and may contribute to the mortality of this condition.

摘要

据报告,8例神经病变患者发生了12次心肺骤停。当时只有1例患者死亡,但另外2例随后在家中突然死亡。骤停时没有心肌梗死、心律失常或低血糖的证据。在大多数发作中,呼吸受到了某种干扰,原因是麻醉、药物或支气管肺炎。其中5次发作发生在麻醉期间或麻醉刚结束后。有人认为,骤停是由呼吸反射缺陷而非心血管反射缺陷引起的。心肺骤停似乎是糖尿病自主神经病变的一个特征,可能会导致这种疾病的死亡率上升。

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1
Cardiorespiratory arrest and diabetic autonomic neuropathy.心肺骤停与糖尿病自主神经病变
Lancet. 1978 Jan 7;1(8054):14-6. doi: 10.1016/s0140-6736(78)90360-4.
2
Cardiorespiratory arrest in diabetic neuropathy.糖尿病性神经病变中的心肺骤停
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3
[Diabetic neuropathies. IV. Autonomous neuropathy. Peripheral sympathetic innervation and the cardiovascular system].
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Am J Clin Nutr. 1978 Feb;31(2):307-9. doi: 10.1093/ajcn/31.2.307.
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Cardiorespiratory arrest in diabetic autonomic neuropathy.糖尿病自主神经病变中的心肺骤停
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Defective innervation of heart in diabetic autonomic neuropathy.糖尿病性自主神经病变中存在心脏神经支配缺陷。
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Cardiorespiratory arrest in a patient with advanced diabetic autonomic neuropathy.晚期糖尿病自主神经病变患者的心肺骤停
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Rev Clin Esp. 1964 Apr 15;93:1-12.

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Mortality experience of a low-income population with young-onset diabetes.低收入人群中青年起病糖尿病的死亡经验。
Diabetes Care. 2012 Mar;35(3):542-8. doi: 10.2337/dc11-1385. Epub 2012 Jan 11.
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J Anesth. 2010 Oct;24(5):739-47. doi: 10.1007/s00540-010-0987-1. Epub 2010 Jul 17.
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Diabetes and cardiovascular autonomic dysfunction: application of animal models.糖尿病与心血管自主神经功能障碍:动物模型的应用
Auton Neurosci. 2009 Jan 28;145(1-2):3-10. doi: 10.1016/j.autneu.2008.10.013. Epub 2008 Dec 2.
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Chronic central leptin infusion restores cardiac sympathetic-vagal balance and baroreflex sensitivity in diabetic rats.慢性中枢性输注瘦素可恢复糖尿病大鼠的心脏交感 - 迷走神经平衡和压力反射敏感性。
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