David H
Gegenbaurs Morphol Jahrb. 1980;126(3):285-92.
During the postnatal development of the liver cells until the 6th month of life, their volume increases to 199% of birth value, whereas the nuclear volume increases to 133%. From the 2nd month onwards, values are reached which correspond essentially to those of adult livers. In order to determine the surface it does not suffice to assume a spheroid to get real values. In addition, the number and size of the microvilli in the areas of the sinusoidal cellular surface and that one near the biliary canaliculi have to be determined. Taking into consideration the assessment of the microvilli the cellular surface increases at birth to 116.4% and in the 6th month to 124.3% of the smooth surface. These morphological findings - development of microvilli on the sinusoidal zone of the plasma membrane (6th month: 2,170) and the one near the biliary canaliculi (6th month: 340.2) - are closely connected with the functional behaviour of those plasma membrane areas.
在肝细胞出生后至6个月大的发育过程中，其体积增加至出生时的199%，而细胞核体积增加至133%。从第2个月起，各项数值基本达到成体肝脏的水平。为了确定表面积，仅假设细胞为球体是不够的，无法得到真实数值。此外，还必须确定肝血窦细胞表面区域和胆小管附近区域的微绒毛数量及大小。考虑到微绒毛的评估，出生时细胞表面增加至光滑表面的116.4%，在第6个月时增加至124.3%。这些形态学发现——质膜肝血窦区微绒毛的发育（第6个月：2170个）和胆小管附近微绒毛的发育（第6个月：340.2个）——与这些质膜区域的功能行为密切相关。
