保泰松与甲苯磺丁脲在人体中的相互作用。
Interaction of phenylbutazone and tolbutamide in man.
作者信息
Szita M, Gachályi B, Tornyossy M, Káldor A
出版信息
Int J Clin Pharmacol Ther Toxicol. 1980 Sep;18(9):378-80.
PMID:7450929
Abstract
Phenylbutazone pretreatment increases tolbutamide half-life, whereas tolbutamide pretreatment decreases phenylbutazone half-life in man. Clinically, phenylbutazone may enhance the hypoglycemic action of tolbutamide, and tolbutamide may reduce the therapeutic effect of phenylbutazone.
摘要
保泰松预处理可延长甲苯磺丁脲的半衰期，而甲苯磺丁脲预处理则会缩短保泰松在人体内的半衰期。临床上，保泰松可能会增强甲苯磺丁脲的降血糖作用，而甲苯磺丁脲可能会降低保泰松的治疗效果。
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Interaction of phenylbutazone and tolbutamide in man.保泰松与甲苯磺丁脲在人体中的相互作用。
Int J Clin Pharmacol Ther Toxicol. 1980 Sep;18(9):378-80.
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