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未受应激的胎儿和新生羔羊的视网膜和脉络膜血流。

Retinal and choroidal blood flow in unstressed fetal and neonatal lambs.

作者信息

Peeters L L, Sheldon R E, Jones M D, Battaglia F C

出版信息

Pediatr Res. 1980 Sep;14(9):1047-52. doi: 10.1203/00006450-198009000-00006.

DOI:10.1203/00006450-198009000-00006
PMID:7454445
Abstract

The relationship between retinal blood flow (RBF) and choroidal blood flow (ChBF) and the oxygen content of arterial blood was investigated in 12 fetal lambs. The postnatal changes in these flows were studied in twelve newborn lambs. RBF and ChBF were determined by means of radioactive microspheres 3 to 10 days after implantation of the injection and sampling catheters. Fetal blood flows were measured at different levels of oxygenation. The postnatal flows were measured while the lamb breathed room air. The fetal data suggest an inverse relationship between RBF and arterial oxygen content. Concomitant changes in fetal ChBF were unrelated to arterial oxygen content. Because of the inverse relationship between RBF and arterial oxygen content, the product of RBF and arterial oxygen content was independent of the state of fetal oxygenation. RBF did not change with birth, whereas ChBF increased. There was no change in RBF with postnatal age whereas ChBF decreased significantly with increasing age.

摘要

在12只胎羊中研究了视网膜血流量(RBF)与脉络膜血流量(ChBF)以及动脉血氧含量之间的关系。在12只新生羔羊中研究了这些血流量的出生后变化。在植入注射和采样导管3至10天后,通过放射性微球测定RBF和ChBF。在不同氧合水平下测量胎羊血流量。在羔羊呼吸室内空气时测量出生后血流量。胎儿数据表明RBF与动脉血氧含量呈负相关。胎儿ChBF的伴随变化与动脉血氧含量无关。由于RBF与动脉血氧含量呈负相关,RBF与动脉血氧含量的乘积与胎儿氧合状态无关。RBF不随出生而变化,而ChBF增加。RBF不随出生后年龄变化,而ChBF随年龄增长显著下降。

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Are severe acute retinopathy of prematurity and severe periventricular leucomalacia both ischaemic insults?重度早产儿急性视网膜病变和重度脑室周围白质软化都是缺血性损伤吗?
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