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脑囊尾蚴病

Cerebral cysticercosis.

作者信息

Percy A K, Byrd S E, Locke G E

出版信息

Pediatrics. 1980 Dec;66(6):967-71.

PMID:7454489
Abstract

In this country, cerebral cysticercosis is not commonly implicated as the etiology of an otherwise uncomplicated seizure disorder occurring during childhood. Nine children with neurologic symptomatology and radiographic (computed tomography) evidence consistent with cerebral cysticercosis have been evaluated. Each patient was born and resided for some period (1 1/2 to 10 years) in an endemic area. Principal symptomatology consisted of a generalized seizure disorder. EEGs were normal in five patients and nonspecific in two. Serologic studies on serum and CSF were negative in 8/9 patients including the single patient requiring surgical intervention for excision of a cysticercal cyst. Cerebral nuclide scanning was not helpful and skull radiography was used to diagnose intracerebral calcifications in six patients. Computed tomography revealed multiple calcifications in six patients and a solitary lesion in one. Five patients had enhancing cystic lesions including three of those with diffuse calcifications. Since the natural history of cerebral cysticercosis presenting in this fashion is benign, symptomatic treatment is often sufficient. Anticonvulsants generally provide adequate seizure control. In one patient, cyst removal was necessary to achieve seizure control. On the basis of this experience, conclusions are (1) that the incidence of cerebral cysticercosis in exposed children is higher than commonly appreciated, and (2) that computed tomography may assist in the establishment of the diagnosis.

摘要

在这个国家,脑囊尾蚴病通常不被认为是儿童期发生的无并发症癫痫发作的病因。我们对9名有神经症状且影像学(计算机断层扫描)证据符合脑囊尾蚴病的儿童进行了评估。每位患者均出生于流行地区并在当地居住了一段时间(1.5至10年)。主要症状为全身性癫痫发作。5例患者脑电图正常,2例无特异性。9例患者中8例血清和脑脊液的血清学检查为阴性,包括1例因切除囊尾蚴囊肿而需要手术干预的患者。脑核素扫描无帮助,6例患者通过头颅X线摄影诊断为脑内钙化。计算机断层扫描显示6例患者有多处钙化,1例有单个病灶。5例患者有强化囊性病灶,其中3例有弥漫性钙化。由于以这种方式出现的脑囊尾蚴病的自然病程是良性的,对症治疗通常就足够了。抗惊厥药一般能充分控制癫痫发作。1例患者需要切除囊肿以控制癫痫发作。基于这一经验,得出的结论是:(1)暴露儿童脑囊尾蚴病的发病率高于普遍认识;(2)计算机断层扫描有助于确诊。

相似文献

1
Cerebral cysticercosis.脑囊尾蚴病
Pediatrics. 1980 Dec;66(6):967-71.
2
Cerebral cysticercosis: surgical considerations.脑囊尾蚴病:手术考量
Bull Clin Neurosci. 1983;48:93-101.
3
Seventy black epileptics. Cysticercosis, computed tomography and electro-encephalography.
S Afr Med J. 1987 Dec 19;72(12):837-8.
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CT diagnosis of cerebral cysticercosis.
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[Cerebral cysticercosis presenting as a solitary cyst. Diagnosis and treatment with CT-guided stereotactic biopsy--case report].
Neurol Med Chir (Tokyo). 1989 Jun;29(6):520-4. doi: 10.2176/nmc.29.520.
6
[Cerebral cysticercosis. About two cases of brain localisation (author's transl)].
Neurochirurgie. 1978;24(2):129-32.
7
Childhood cerebral cysticercosis: clinical features and computed tomographic findings in 89 Mexican children.儿童脑囊尾蚴病:89名墨西哥儿童的临床特征及计算机断层扫描结果
Can J Neurol Sci. 1982 Nov;9(4):401-7. doi: 10.1017/s0317167100044309.
8
Cysticercosis of the central nervous system. I. Surgical treatment of cerebral cysticercosis: a 23 years experience in the Hospital das Clínicas of Ribeirão Preto Medical School.中枢神经系统囊尾蚴病。I. 脑囊尾蚴病的外科治疗:里贝朗普雷图医学院临床医院23年的经验。
Arq Neuropsiquiatr. 1994 Jun;52(2):166-86. doi: 10.1590/s0004-282x1994000200006.
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[Criteria for the diagnosis of epilepsy caused by cerebral cysticercosis in a population of recruits].
Vojnosanit Pregl. 1989 Nov-Dec;46(6):420-7.
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Epilepsy as a manifestation of neurocysticercosis.
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引用本文的文献

1
Enzyme-linked immunosorbent assay for the diagnosis of cerebral cysticercosis.用于诊断脑囊尾蚴病的酶联免疫吸附测定
J Clin Microbiol. 1984 Oct;20(4):775-9. doi: 10.1128/jcm.20.4.775-779.1984.
2
Cysticercosis update.囊尾蚴病最新进展
West J Med. 1984 Jun;140(6):901-4.
3
Radiology--including computed tomography--of parasitic diseases of the central nervous system.
Neurosurg Rev. 1983;6(3):129-37. doi: 10.1007/BF01742764.
4
Cerebral cysticercosis.脑囊尾蚴病
Neurosurg Rev. 1983;6(3):119-27. doi: 10.1007/BF01742763.
5
The computed tomographic spectrum of cerebral cysticercosis.脑囊尾蚴病的计算机断层扫描影像谱
J Natl Med Assoc. 1985 Jul;77(7):553-60.