Volterrani F, Sigurtà D, Gardani G, Uslenghi C, Centenaro G, Chiesa F, Molinari R
Radiol Med. 1980 Mar;66(3):131-40.
The clinical classification of oral carcinomas presents some points still under discussion. In other respects the main questions about the treatment of these cancers could be resolved by cooperative clinical trials which impose the definition of a common clinical language. With a system based on an original computer program for the compiling, store and process essential data on cancer diseases we analyzed 736 consecutive and unselected oral carcinomas and we studied the prognostic value of main clinical factors. In our series, the main prognostic factors are tumor size, clinical appearance of the primary and clinical status of neck nodes. Sex, age and histological grade are unimportant. From our study we propose to complete the TN classification with two useful clinical criteria distinguishing the exophytic or minimally infiltrating tumors from the deeply infiltrating (greater than 1 cm) and the large metastatic omolateral nodes from the small ones (phi less than 3 cm).
口腔癌的临床分类仍存在一些有待探讨的问题。在其他方面，关于这些癌症治疗的主要问题可以通过合作临床试验来解决，这些试验需要确立一种通用临床语言的定义。我们使用一个基于原始计算机程序的系统来收集、存储和处理癌症疾病的基本数据，分析了736例连续且未经筛选的口腔癌病例，并研究了主要临床因素的预后价值。在我们的研究系列中，主要的预后因素是肿瘤大小、原发灶的临床表现以及颈部淋巴结的临床状况。性别、年龄和组织学分级并不重要。根据我们的研究，我们建议用两个有用的临床标准来完善TN分类，以区分外生性或微浸润性肿瘤与深度浸润性肿瘤（大于1厘米），以及大的同侧转移性淋巴结与小的淋巴结（直径小于3厘米）。
