Tung L C, Häring R, Waldschmidt J, Weber D
Zentralbl Chir. 1980;105(18):1195-205.
19 extracorporeal liver perfusions have been performed for treating hepatic coma in 11 patients. No improvement was found in 3 patients, improvement in 8.5 of these 8 patients recovered full consciousness. All 7 patients with pre-existent liver disease died. Of 4 patients without pre-existent liver disease, 2 were discharged and are still alive. At present, extracorporeal liver perfusion seems to be the most promising treatment for hepatic coma. It should be undertaken at Stage IV and at Stage III with increasing prothrombin time. Pre-existent liver disease should be excluded before by laparoscopy.
已对11例患者进行了19次体外肝脏灌注治疗肝昏迷。3例患者无改善,8例有改善,其中8.5例恢复了完全意识。所有7例原有肝病的患者均死亡。4例无原有肝病的患者中,2例出院且仍存活。目前,体外肝脏灌注似乎是治疗肝昏迷最有前景的方法。应在IV期以及凝血酶原时间延长的III期进行。在进行之前应通过腹腔镜检查排除原有肝病。