MacLennan W J, Hall M R, Timothy J I, Robinson M
Age Ageing. 1980 Aug;9(3):188-92. doi: 10.1093/ageing/9.3.188.
Grip strength and fat-free mass (FFM) were measured in 158 men and 112 women of 65 years and over living at home. There was a striking decline in grip strength with increasing age in both men and women. A marginal decline in FFM was not statistically significant. Multiple regression analysis suggested that age had an effect on grip strength which was independent of FFM. An explanation for this pattern might be that with ageing an increasing proportion of skeletal muscle is replaced by fibrous tissue, so that, although there is striking reduction in muscle power, there is only a marginal reduction in FFM.
对158名65岁及以上的居家男性和112名65岁及以上的居家女性测量了握力和去脂体重（FFM）。男性和女性的握力均随年龄增长而显著下降。去脂体重的轻微下降无统计学意义。多元回归分析表明，年龄对握力有影响，且该影响独立于去脂体重。这种模式的一种解释可能是，随着年龄增长，越来越多的骨骼肌被纤维组织取代，因此，尽管肌肉力量显著下降，但去脂体重仅略有下降。
