Hilal S K, Chang C H
Neuroradiology. 1978;16:537-9. doi: 10.1007/BF00395353.
A previously unsuspected linear relationship between the initial density and the amount of uptake of various tumors is described. As a rule, initially radiodense neoplasms enhance less than radiolucent neoplasms. For a given amount of enhancement, meningiomas are initially more radiodense than metastases; also, breast metastases are more radiodense than lung metastases. The density versus uptake curve tends to show certain specificity for a given type of neoplasm. Absolute differentiation of histologic types is still not possible on the basis of these curves. The correlation, however, is interesting and seems to be related to the amount of damage to the blood-brain barrier and the degree of calcification, vascularity, and cellularity of the various tumors. With improved precision of scanners the specificity of the CT image may be improved.
本文描述了各种肿瘤的初始密度与摄取量之间此前未被怀疑的线性关系。通常，初始放射性密度高的肿瘤增强程度低于放射性密度低的肿瘤。对于给定的增强量，脑膜瘤的初始放射性密度高于转移瘤；此外，乳腺转移瘤的放射性密度高于肺转移瘤。密度与摄取曲线对于给定类型的肿瘤往往显示出一定的特异性。基于这些曲线仍无法对组织学类型进行绝对区分。然而，这种相关性很有趣，似乎与血脑屏障的损伤程度以及各种肿瘤的钙化、血管化和细胞化程度有关。随着扫描仪精度的提高，CT图像的特异性可能会得到改善。
