Belal A, House W F, Antunez J C
Am J Otol. 1980 Jan;1(3):147-50.
The histopathologic findings in the temporal bones of two patients who underwent a cryo-otic-perotic shunt procedure are reported. Morphologic changes in the inner ear were limited to the area of cryoprobe application on the promontory. The hook region of the cochlear duct showed severe atrophy of the spiral ligament, stria vascularis, and sensorineural structures. The ampulla of the posterior semicircular canal showed fibrosis in the perilymphatic space and ruptured membranous walls. No changes were found in the rest of the vestibular labyrinth or in the facial nerve. The long-term improvement in these patients' symptoms, i.e., eight years in one and four years in the other, could only be explained on the basis that endolymph and perilymph mix across intact, nonfunctioning membranes of the cochlear duct or through, presumably antemortem, ruptures of the posterior semicircular canal ampulla.
报告了两名接受冷冻耳-岩骨分流术患者颞骨的组织病理学发现。内耳的形态学变化仅限于在岬部应用冷冻探头的区域。蜗管的钩区显示螺旋韧带、血管纹和感觉神经结构严重萎缩。后半规管壶腹在淋巴间隙出现纤维化，膜壁破裂。在前庭迷路的其余部分或面神经中未发现变化。这些患者症状的长期改善，即一名患者为八年，另一名患者为四年，只能基于内淋巴和外淋巴通过蜗管完整但无功能的膜混合或通过后半规管壶腹可能在生前发生的破裂来解释。
