Tannières M L, Levante A, Raggeneau J L, Lienhart A
Anesth Analg (Paris). 1980;37(5-6):305-9.
Air embolism in neurosurgery, in the sitting position, are not rare. They depend on the type of surgery (more frequent in operations on the posterior fossa), on the mode of ventilation, and most of all on the criteria for detection (clinical, electrocardiographic, ultrasonic, capnographic of haemodynamia). They depend as well upon the degree of tilt, of intrathoracic and intracardiac pressures (right auricle) and of the gas mixture administered (nitrous oxide increases their size owing to its poor blood solubility). The way of entry is venous, but it is certain that they can pass into the systemic circulation (their passage through the lungs is debated). According to their size, the speed of injection and the subject's previous condition they may affect: --the lungs: precapillary pulmonary artery hypertension, and even pulmonary oedema, --the heart, mainly through the fall of venous return, --the brain anoxia, followed by cerebral oedema, leading to early neurologic disturbances and possibly severe sequellae. Those symptoms are due to the gas embolism itself, but also to microthrombi of fibrin and disturbances of vascular membrane permeability.
神经外科手术中,坐位时空气栓塞并不罕见。其发生取决于手术类型(在后颅窝手术中更常见)、通气模式,最重要的是取决于检测标准(临床、心电图、超声、血流动力学二氧化碳描记法)。它还取决于倾斜程度、胸内和心内压力(右心房)以及所给予的气体混合物(氧化亚氮由于其血液溶解度低会增大气泡大小)。空气进入途径为静脉,但它们肯定能进入体循环(其通过肺部的情况存在争议)。根据气泡大小、注入速度和患者先前状况,它们可能会影响:——肺部:肺小动脉前高血压,甚至肺水肿;——心脏,主要是通过静脉回流量减少;——脑部缺氧,继而导致脑水肿,引发早期神经功能障碍并可能留下严重后遗症。这些症状不仅是由气体栓塞本身引起的,还与纤维蛋白微血栓和血管膜通透性紊乱有关。