培养细胞中的脂质代谢：关于正常及纯合子家族性高胆固醇血症皮肤成纤维细胞中脂蛋白催化的胆固醇逆向转运的研究 - Suppr | 超能文献

Lipid metabolism in cultured cells: studies on lipoprotein-catalyzed reverse cholesterol transport in normal and homozygous familial hypercholesterolemic skin fibroblasts.

作者信息

Wu J D, Bailey J M

出版信息

Arch Biochem Biophys. 1980 Jul;202(2):467-73. doi: 10.1016/0003-9861(80)90451-8.

DOI:10.1016/0003-9861(80)90451-8

Abstract

摘要

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Lipid metabolism in cultured cells: studies on lipoprotein-catalyzed reverse cholesterol transport in normal and homozygous familial hypercholesterolemic skin fibroblasts.培养细胞中的脂质代谢：关于正常及纯合子家族性高胆固醇血症皮肤成纤维细胞中脂蛋白催化的胆固醇逆向转运的研究

Arch Biochem Biophys. 1980 Jul;202(2):467-73. doi: 10.1016/0003-9861(80)90451-8.

2

Characterization of hepatic low density lipoprotein binding and cholesterol metabolism in normal and homozygous familial hypercholesterolemic subjects.正常及纯合子家族性高胆固醇血症患者肝脏低密度脂蛋白结合及胆固醇代谢特征

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Quantification of low density lipoprotein binding and cholesterol accumulation by single human fibroblasts using fluorescence microscopy.

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Monensin and brefeldin A inhibit high density lipoprotein-mediated cholesterol efflux from cholesterol-enriched cells. Implications for intracellular cholesterol transport.莫能菌素和布雷菲德菌素A抑制高密度脂蛋白介导的胆固醇从富含胆固醇的细胞中流出。对细胞内胆固醇转运的影响。

J Biol Chem. 1995 Mar 17;270(11):5891-900. doi: 10.1074/jbc.270.11.5891.

5

[Disorders of lipoprotein and cholesterol metabolism in familial hypercholesterolemia].家族性高胆固醇血症中的脂蛋白和胆固醇代谢紊乱

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6

Induction of low density lipoprotein receptor synthesis by high density lipoprotein in cultures of human skin fibroblasts.

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Cholesterol efflux from cultured skin fibroblasts in 12 patients clinically heterozygous for familial hypercholesterolemia.

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A receptor-mediated pathway for cholesterol homeostasis.胆固醇稳态的受体介导途径。

Science. 1986 Apr 4;232(4746):34-47. doi: 10.1126/science.3513311.

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WHHL-rabbit: a low density lipoprotein receptor-deficient animal model for familial hypercholesterolemia.WHHL兔：一种用于家族性高胆固醇血症的低密度脂蛋白受体缺陷动物模型。

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Transfer of lipids to high-density lipoprotein (HDL) is altered in patients with familial hypercholesterolemia.家族性高胆固醇血症患者的脂质向高密度脂蛋白（HDL）的转移发生改变。

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引用本文的文献

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Regulation of sterol transport in human microvascular endothelial cells.人微血管内皮细胞中固醇转运的调控

J Cell Biol. 1982 Aug;94(2):350-4. doi: 10.1083/jcb.94.2.350.

2

Evidence for a lipoprotein carrier in human plasma catalyzing sterol efflux from cultured fibroblasts and its relationship to lecithin:cholesterol acyltransferase.人血浆中一种催化培养成纤维细胞胆固醇流出的脂蛋白载体的证据及其与卵磷脂胆固醇酰基转移酶的关系。

Proc Natl Acad Sci U S A. 1981 Jun;78(6):3911-4. doi: 10.1073/pnas.78.6.3911.