Iqbal M Z, Liebson P R
Arch Intern Med. 1981 Feb;141(2):247-9. doi: 10.1001/archinte.141.2.247.
A patient had right ventricular infarction complicated by cardiogenic shock. Volume expansion along with high doses of dopamine hydrochloride successfully alleviated hypotension in this patient. However, he had persistent mental obtundation and low cardiac output, and adverse chronotropic responses to high doses of dopamine developed. Counterpulsation effectively maintained an adequate arterial pressure and dopamine therapy was discontinued. Counterpulsation, however, failed to augment cardiac output. Simultaneous use of dobutamine hydrochloride along with counterpulsation was associated with a noticeable increase in cardiac output. To our knowledge, this is the first reported case of right ventricular infarct complicated by shock in which the simultaneous use of counterpulsation and dobutamine therapy resulted in a substantial increase in cardiac output.
一名患者发生右心室梗死并伴有心源性休克。扩容联合大剂量盐酸多巴胺成功缓解了该患者的低血压。然而,他仍持续存在精神迟钝和心输出量低的情况,并且对大剂量多巴胺出现了不良的变时反应。反搏有效地维持了足够的动脉压,于是停用了多巴胺治疗。然而,反搏未能增加心输出量。盐酸多巴酚丁胺与反搏同时使用使心输出量显著增加。据我们所知,这是首例右心室梗死合并休克且反搏与多巴酚丁胺治疗同时使用导致心输出量大幅增加的病例报告。