银屑病光化学疗法中血浆8-甲氧基补骨脂素的浓度。

Plasma 8-methoxypsoralen concentrations in photochemotherapy of psoriasis.

作者信息

Stevenson I H, Kenicer K J, Johnson B E, Frain-Bell W

出版信息

Br J Dermatol. 1981 Jan;104(1):47-51. doi: 10.1111/j.1365-2133.1981.tb01710.x.

DOI:10.1111/j.1365-2133.1981.tb01710.x

Abstract

A quantitative study of 8-methoxypsoralen plasma profiles in patients with psoriasis undergoing photochemotherapy shows that a poor response to the treatment may be explained in terms of abnormal pharmacokinetic behaviour. However, not all 'poor responders' exhibit an abnormal pattern and for these an alternative explanation is required.

摘要

一项针对接受光化学疗法的银屑病患者的8-甲氧基补骨脂素血浆图谱的定量研究表明，治疗反应不佳可能是由异常的药代动力学行为所致。然而，并非所有“反应不佳者”都表现出异常模式，对于这些患者需要另寻解释。