English C J, Poller L, Burslem R W
Br J Obstet Gynaecol. 1981 Feb;88(2):133-7. doi: 10.1111/j.1471-0528.1981.tb00956.x.
The procoagulant properties of amniotic fluid have been studied in samples taken throughout pregnancy and the results correlated with the lecithin/sphingomyelin ratio: acceleration effects on the prothrombin time. Russell's viper venom test, activated partial thromboplastin time and specific factor VII and X assays and contact acceleration. Although amniotic fluid is shown to function as a complete thromboplastin and to activate factor X directly, none of these tests of procoagulant activity of amniotic fluid is a reliable index of fetal lung maturity.
在整个孕期采集的羊水样本中研究了其促凝特性，并将结果与卵磷脂/鞘磷脂比值相关联：对凝血酶原时间有加速作用。蝰蛇毒时间试验、活化部分凝血活酶时间以及特定因子VII和X测定以及接触加速试验。尽管羊水被证明可作为一种完整的凝血活酶发挥作用并直接激活因子X，但这些羊水促凝活性检测方法均不是胎儿肺成熟度的可靠指标。
