Cochrane J P, Yarnold J R, Slack W W
Br J Surg. 1981 Jan;68(1):25-8. doi: 10.1002/bjs.1800680108.
The outcome of serious radiation injuries to the pelvic viscera in 400 patients treated by radiotherapy for carcinoma of the uterus between January 1974 and December 1978 has been reviewed. Twenty-eight instances of serious radiation damage have been found, 13 of predominantly small bowel damage, 11 of predominantly large bowel damage and 4 of bladder damage. Many patients had involvement at multiple sites. Fourteen patients have died, and 9 survivors have artificial abdominal stomas. Leaking anastomoses and progressive sepsis were major problems in the postoperative period and could be related either to inadequate resection of irradiated bowel or to damage to other organs at operation. The possibilities of earlier diagnosis and better surgical procedures are discussed.
对1974年1月至1978年12月期间因子宫癌接受放射治疗的400例患者盆腔脏器严重放射损伤的结果进行了回顾。发现28例严重放射损伤，其中13例主要为小肠损伤，11例主要为大肠损伤，4例为膀胱损伤。许多患者有多个部位受累。14例患者死亡，9名幸存者有腹部人工造口。术后吻合口漏和进行性脓毒症是主要问题，可能与受照射肠段切除不充分或手术中其他器官受损有关。文中讨论了早期诊断和更好手术方法的可能性。
