Ebbesson S O
Cell Tissue Res. 1980;213(2):179-212. doi: 10.1007/BF00234781.
Recently discovered neocortical equivalents in anamniotes and certain patterns of interspecific variability in brain organization provide new insights into evolutionary and ontogenetic mechanisms of development. The new data suggest that nervous systems become more complex, not by one system invading another, but by a process of parcellation that involves the selective loss of connections of the newly formed daughter aggregates and subsystems. The parcellation process is reflected in the normal ontogenetic development of the CNS in a given species and can be manipulated, to a certain extent, by deprivation or surgically induced sprouting. The parcellation theory allows certain predictions about the range of variation of a given system at all levels of analysis including the cellular and aggregate levels. For example, the interspecific variability in organization of cortical columns, thalamic nuclei, cortical areas and tectal layers can be explained. The findings, summarized here, suggest that diffuse, undifferentiated systems existed in the beginning of vertebrate evolution and that during the evolution of complex behaviors, and analytical capacities related to these behaviors, a range of patterns of neural systems evolved that relate to these functions. One principle underlying the growth, differentiation and multiplication of neural systems appears to be the process of parcellation as defined by the theory.
最近在无羊膜动物中发现的新皮质等效物以及脑组织中某些种间变异模式，为发育的进化和个体发育机制提供了新的见解。新数据表明，神经系统变得更加复杂，不是通过一个系统侵入另一个系统，而是通过一种分割过程，该过程涉及新形成的子聚集体和子系统连接的选择性丧失。分割过程反映在给定物种中枢神经系统的正常个体发育中，并且在一定程度上可以通过剥夺或手术诱导的发芽来操纵。分割理论允许对给定系统在包括细胞和聚集体水平在内的所有分析水平上的变异范围进行某些预测。例如，皮质柱、丘脑核、皮质区域和顶盖层组织的种间变异可以得到解释。此处总结的研究结果表明，在脊椎动物进化开始时存在弥散性、未分化的系统，并且在复杂行为以及与这些行为相关的分析能力的进化过程中，一系列与这些功能相关的神经系统模式得以进化。神经系统生长、分化和增殖的一个基本原则似乎是该理论所定义的分割过程。
