Rengo F, Volpe M, Ricciardelli B, Morrone G, Chiariello M, Trimarco B, Condorelli M
G Ital Cardiol. 1980;10(1):18-23.
In this study we have investigated the effects of the stellate ganglion electrostimulation on the perfusion pressure of coronary vascular bed perfused at constant flow. We always observed systemic hypertension and two kinds of response in the coronary district: vasodilatation or vasoconstriction. These responses were blocked by propranolol and phentolamine i.a. administration respectively, while both the phenomena were blocked by i.v. infection of guanethidine. These results seem to suggest that nervous sympathetic stimulation induces catecholamines release by means of either pregangliar adrenergic fibers directed to coronary vessels either postgangliar adrenergic fibres directed to the myocardium. The occurrence of vasodilatation or vasoconstriction could be explained by the prevalent stimulation of myocardial or coronary adrenoceptors.
在本研究中,我们研究了星状神经节电刺激对以恒定流量灌注的冠状血管床灌注压的影响。我们始终观察到全身性高血压以及冠状区的两种反应:血管舒张或血管收缩。这些反应分别被静脉注射普萘洛尔和酚妥拉明阻断,而这两种现象均被静脉注射胍乙啶阻断。这些结果似乎表明,神经交感刺激通过支配冠状血管的节前肾上腺素能纤维或支配心肌的节后肾上腺素能纤维诱导儿茶酚胺释放。血管舒张或血管收缩的发生可以通过心肌或冠状肾上腺素能受体的普遍刺激来解释。