Zhao Y
Department of Anesthesiology, Tohoku University School of Medicine, Sendai.
Masui. 1995 Jul;44(7):937-43.
To evaluate effects of stellate ganglion block (SGB) on coronary circulation under coronary occlusion, the changes in cardiac function and tissue blood flow in the myocardial ischemic area after right and left SGB were observed in the dogs. Tissue blood flow in the myocardial ischemic area measured with laser doppler flowmeter showed no significant change after right or left SGB. In the right SGB group, heart rate, circumflex branch blood flow and rate pressure product decreased significantly (P < 0.01); end-diastolic pressure increased slightly (P < 0.05); myocardial oxygen extraction rate showed no significant change. On the other hand, in the left SGB group, heart rate, circumflex branch blood flow and rate pressure product showed no significant changes, while end-diastolic pressure and myocardial oxygen extraction rate increased significantly (P < 0.05). These data suggest that although right SGB might be useful to improve the oxygen demand-supply relation, left SGB does not improve the oxygen demand-supply relation and might increase the risk of myocardial ischemia.
为评估星状神经节阻滞（SGB）对冠状动脉闭塞情况下冠脉循环的影响，观察了犬左右侧SGB后心肌缺血区域的心功能和组织血流变化。用激光多普勒血流仪测量的心肌缺血区域组织血流在左右侧SGB后均无显著变化。右侧SGB组中，心率、回旋支血流和心率血压乘积显著降低（P<0.01）；舒张末期压力略有升高（P<0.05）；心肌氧摄取率无显著变化。另一方面，左侧SGB组中，心率、回旋支血流和心率血压乘积无显著变化，而舒张末期压力和心肌氧摄取率显著升高（P<0.05）。这些数据表明，虽然右侧SGB可能有助于改善氧供需关系，但左侧SGB并不能改善氧供需关系，且可能增加心肌缺血风险。
