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急性心肌梗死患者心输出量的超声心动图评估(作者译)

[Echocardiographic evaluation of cardiac output in patients with acute myocardial infarction (author's transl)].

作者信息

Nador F, De Martini M, Binda A, Salmaso G C, Radrizzani D, Lotto A

出版信息

G Ital Cardiol. 1980;10(8):944-51.

PMID:7461352
Abstract

Echocardiography is a non invasive technique particularly useful to assess both hemodynamics and left ventricular performances; different methods have been proposed to evaluate echocardiographically the cardiac output. The aim of this work is to suggest a new method (planimetry of the area enclosed by echoes from the mitral valve) stating its advantages and limits and to test three already known methods (cubes method, method of Lalani and Lee, method of Rasmussen and coll.) comparing them to thermodilution. In 24 patients admitted in our Coronary Care Unit for acute myocardial infarction 30 measurements have been performed simultaneously with echocardiography and thermodilution. Statistical analysis (correlation coefficient with the method of the square minimums and Student's 't') of the results has shown that the cubes method is unprecise (P = NS) and unbiased (d = 0.97 +/- 15.46); Lalani-Lee method is unprecise (P = NS) and biased (d = 9.64 +/- 21.36) by a systematic underestimate error concealed by the poor precision; Rasmussen and coll. method is precise (P < 0.01) but biased (d = --3.03 +/- 5.5), the systematic mistake being entirely due to the group of patients with abnormal hemodynamics. Our method is precise (P < 0.01) and unbiased (d = --0.04 +/- 9.62) in patients both with normal and abnormal hemodynamics. Therefore this method offers the following advantages: 1) it is unbiased, even in the presence of abnormal left ventricular performance; 2) it is sufficiently precise, having a correlation coefficient with thermodilution of r = 0.80; 3) it measures directly the amount of flow due to the atrial systole; 4) the measurement is rapid and hardly biased by the reader.

摘要

超声心动图是一种非侵入性技术,对评估血流动力学和左心室功能特别有用;已经提出了不同的方法来通过超声心动图评估心输出量。这项工作的目的是提出一种新方法(二尖瓣回声所包围区域的面积测量法),说明其优点和局限性,并测试三种已知方法(立方体积法、拉腊尼和李法、拉斯穆森等人的方法),并将它们与热稀释法进行比较。在我们冠心病监护病房收治的24例急性心肌梗死患者中,同时进行了30次超声心动图和热稀释测量。对结果的统计分析(与最小二乘法和学生t检验的相关系数)表明,立方体积法不精确(P=无显著性差异)且无偏差(d=0.97±15.46);拉腊尼-李法不精确(P=无显著性差异)且有偏差(d=9.64±21.36),由于精度差掩盖了系统性低估误差;拉斯穆森等人的方法精确(P<0.01)但有偏差(d=-3.03±5.5),系统性错误完全归因于血流动力学异常的患者组。我们的方法在血流动力学正常和异常的患者中都精确(P<0.01)且无偏差(d=-0.04±9.62)。因此,该方法具有以下优点:1)即使在左心室功能异常的情况下也无偏差;2)足够精确,与热稀释法的相关系数r=0.80;3)直接测量心房收缩期的血流量;4)测量迅速,且受读者影响很小。

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