Kitamura K
J Immunol Methods. 1980;39(3):277-83. doi: 10.1016/0022-1759(80)90062-9.
Delayed-type hypersensitivity lesions have been difficult to evaluate objectively in the mouse. They are usually evaluated by measurement of footpad swelling or increased ear thickness after challenge with antigen. I have developed a footpad weight assay method which reduces the observer's error and the instrumental error. This method is reliable for the assessment of delayed-type hypersensitivity reactions when results are expressed as weight increase or weight ratio calculated on challenged and unchallenged footpad.
在小鼠中，迟发型超敏反应损伤一直难以进行客观评估。通常通过测量抗原激发后足垫肿胀或耳厚度增加来评估。我开发了一种足垫重量测定方法，该方法减少了观察者误差和仪器误差。当将结果表示为激发和未激发足垫的重量增加或重量比时，这种方法对于评估迟发型超敏反应是可靠的。
