Mazur J M, Stauffer E S
J Fam Pract. 1981 Feb;12(2):333-41.
The family physician will rarely see patients with bone tumors; however, when bone tumors do arise, they can be devastating as they unfortunately occur in young patients and are among the most malignant of lesions. The diagnosis of a bone tumor should be suspected if there is deep aching pain, a mass, or a pathological fracture. X-ray films usually lead to the diagnosis and help distinguish malignant from benign lesions. benign tumors are relatively small, do not break out of the bone, and leave the cortex intact and the soft tissue uninvolved. Malignant tumors are large, break out of the bone, and involve the soft tissues. In general, benign tumors are treated with biopsy, local excision, or curettage with bone grafting. Malignant tumors require much more extensive surgery including wide radical excision (probably amputation), chemotherapy, and/or radiation therapy as indicated.
家庭医生很少会接诊患有骨肿瘤的患者;然而,当骨肿瘤确实出现时,它们可能具有毁灭性,因为不幸的是,这些肿瘤多发生在年轻患者身上,且属于最恶性的病变之一。如果出现深部隐痛、肿块或病理性骨折,就应怀疑骨肿瘤的诊断。X线片通常能得出诊断结果,并有助于区分恶性病变和良性病变。良性肿瘤相对较小,不会突破骨质,皮质保持完整,软组织未受侵犯。恶性肿瘤体积较大,会突破骨质并累及软组织。一般来说,良性肿瘤通过活检、局部切除或刮除并植骨来治疗。恶性肿瘤则需要更广泛的手术,包括广泛根治性切除(可能需要截肢)、化疗和/或根据具体情况进行放射治疗。